Genome-wide SNP-based linkage analysis of tuberculosis in Thais
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چکیده
منابع مشابه
SNP markers-based map construction and genome-wide linkage analysis in Brassica napus.
An Illumina Infinium array comprising 5306 single nucleotide polymorphism (SNP) markers was used to genotype 175 individuals of a doubled haploid population derived from a cross between Skipton and Ag-Spectrum, two Australian cultivars of rapeseed (Brassica napus L.). A genetic linkage map based on 613 SNP and 228 non-SNP (DArT, SSR, SRAP and candidate gene markers) covering 2514.8 cM was const...
متن کاملKnowledge-Based Analysis of Genome-Wide SNP Scanning Data
Many million dollar-scale genome-wide association (GWA) studies are currently underway for identifying genetic elements involved in complex disorders. However, prevailing GWA data analysis methods are focusing on the association of individual SNP alleles with a complex disease, although multiple alleles are involved by definition. Available data suggest few SNP alleles can pass the genomewide m...
متن کاملGenome wide high density SNP-based linkage analysis of childhood absence epilepsy identifies a susceptibility locus on chromosome 3p23-p14
Childhood absence epilepsy (CAE) is an idiopathic generalised epilepsy (IGE) characterised by typical absence seizures manifested by transitory loss of awareness with 2.5-4 Hz spike-wave complexes on ictal EEG. A genetic component to the aetiology is well recognised but the mechanism of inheritance and the genes involved are yet to be fully established. A genome wide single nucleotide polymorph...
متن کاملWeighted SNP Set Analysis in Genome-Wide Association Study
Genome-wide association studies (GWAS) are popular for identifying genetic variants which are associated with disease risk. Many approaches have been proposed to test multiple single nucleotide polymorphisms (SNPs) in a region simultaneously which considering disadvantages of methods in single locus association analysis. Kernel machine based SNP set analysis is more powerful than single locus a...
متن کاملMeta-analysis of genome-wide linkage studies in celiac disease.
OBJECTIVE A meta-analysis of genome-wide linkage studies allows us to summarize the extensive information available from family-based studies, as the field moves into genome-wide association studies. METHODS Here we apply the genome scan meta-analysis (GSMA) method, a rank-based, model-free approach, to combine results across eight independent genome-wide linkages performed on celiac disease ...
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ژورنال
عنوان ژورنال: Genes & Immunity
سال: 2008
ISSN: 1466-4879,1476-5470
DOI: 10.1038/gene.2008.81